Protein name:
Protein cereblon ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Component of a DCX (DDB1-CUL4-X-box) protein ligase complex, at least composed of CRBN, CUL4A, DDB1 and RBX1. Interacts with KCNT1.
Function:
Component of some DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8. In the complex, may act as a substrate receptor. Regulates the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1.
Subcellular Location:
Cytoplasm
Nucleus
Membrane
Peripheral membrane protein
Protein Attributes:
50:
MAGEGDPEDA | AHNMGNHLPL | LPAEEEEEDE | IEMEVEDQDN | KEPKKPNIIN |
100:
FDTSLPTSHT | YLGSDMEEFH | GRTLHDDDSC | PVIPVLPQVV | MTLIPGQTLP |
150:
LQLFSPQEVS | MVRNLIQKDR | TFAVLAYSNV | QEREAQFGTT | AEIYAYREEQ |
200:
DFGIEVVKVK | AIGRQRFKVL | EIRTQSDGIQ | QAKVQILPEC | VLPSTMSAVQ |
250:
LESLNKCRIF | PSKPVSWEDQ | CSYKWWQKYQ | KRKFHCANLT | SWPRWLYSLY |
300:
DAETLMDRIK | KQLREWDENL | KEDSLPSNPI | DFSYRVAACL | PIDDVLRIQL |
350:
LKIGSAIQRL | RCELDIMNKC | TSLCCKQCQE | TEITTKNEIF | SLSLCGPMAA |
400:
YVNPHGYVHE | TLTVYKASNL | NLIGRPSTDH | SWFPGYAWTI | AQCRICASHI |
444:
GWKFTATKKD | MSPQKFWGLT | RSALLPTIPD | TEDDISPDKV | ILCL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Chicken
Mouse
Rat
ELISA Kit for Bovine Protein cereblon
ELISA Kit for Bovine Protein cereblon
ELISA Kit for Bovine Protein cereblon
ELISA Kit for Bovine Protein cereblon
ELISA Kit for Bovine Protein cereblon
CLIA Kit for Bovine Protein cereblon
CLIA Kit for Bovine Protein cereblon
CLIA Kit for Bovine Protein cereblon
CLIA Kit for Bovine Protein cereblon
CLIA Kit for Bovine Protein cereblon
Polyclonal Antibody for Bovine Protein cereblon
Polyclonal Antibody for Bovine Protein cereblon
Polyclonal Antibody for Bovine Protein cereblon
Polyclonal Antibody for Bovine Protein cereblon
Polyclonal Antibody for Bovine Protein cereblon
Monoclonal Antibody for Bovine Protein cereblon
Monoclonal Antibody for Bovine Protein cereblon
Monoclonal Antibody for Bovine Protein cereblon
Monoclonal Antibody for Bovine Protein cereblon
Monoclonal Antibody for Bovine Protein cereblon
Protein for Bovine Protein cereblon
Protein for Bovine Protein cereblon
Protein for Bovine Protein cereblon
Protein for Bovine Protein cereblon
Protein for Bovine Protein cereblon
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Hippocampus .